Project Details

Funding

Indian Council of Medical Research

May 2018 to March 2020

Project Brief

In this study, we conducted a thorough analysis of cholera infection India by synthesizing data from various sources. This included a nationally representative serosurvey and information from clinical surveillance, outbreak reports, and national risk factors. A composite vulnerability index, considering seroincidence, household sanitation, safe drinking water, and poverty, was developed to identify cholera vulnerable areas in the country.

The study revealed the widespread presence of cholera infection across all five regions in India. It also underscored the geographic variability of cholera risk and highlighted specific regions requiring targeted interventions to mitigate the impact of the disease. The findings have contributed valuable insights for public health planning and interventions, emphasizing the importance of addressing region-specific vulnerabilities in the fight against cholera in India.

Role & Responsbilities

I contributed to the design, analysis, and interpretation of data examining cholera risk across India by integrating national serosurvey findings with epidemiologic and social determinant datasets, evidence synthesis from prior publications and data from ongoing surveillance of outbreaks of acute watery diarrhea. My primary role involved harmonizing multiple data sources, supporting the development of the analytical framework, and leading components of the statistical and spatial analyses that linked serologic markers with geographic and socioeconomic risk factors. I also participated in manuscript drafting and critical revision, ensuring that the findings were positioned to inform cholera surveillance and public health policy in India.

Peer-Reviewed Publications

Kanungo S, Nandy RK, Talukdar R, Murhekar M, Azman AS, Hegde ST, Chatterjee P, Chakraborty D, Das M, Kamaraj P, Kumar MS. Analysis of Cholera Risk in India: Insights from 2017–18 Serosurvey Data Integrated with Epidemiologic data and Societal Determinants from 2015–2019. PLOS Neglected Tropical Diseases. 2024 Sep 3;18(9):e0012450.
Chatterjee P, Kanungo S, Bhattacharya SK, Dutta S. Mapping cholera outbreaks and antibiotic resistant Vibrio cholerae in India: An assessment of existing data and a scoping review of the literature. Vaccine. 2020 Feb 29;38:A93-104.
Panda S, Chatterjee P, Deb A, Kanungo S, Dutta S. Preventing cholera in India: Synthesizing evidences through a systematic review for policy discussion on the use of oral cholera vaccine. Vaccine. 2020 Feb 29;38 Suppl 1:A148-A156. doi: 10.1016/j.vaccine.2019.07.029. Epub 2019 Aug 9. PMID: 31405636.
Debnath F, Deb AK, Sinha A, Chatterjee P, Dutta S. Cleanliness: Success in Water Borne Diseases. The Indian Journal of Medical Research. 2019 Jan;149(Suppl 1):S105.
Chatterjee P, Kanungo S, Dutta S. Challenges for programmatic implementation of killed whole cell oral cholera vaccines for prevention and control of cholera: a meta-opinion. Expert Opinion on Biological Therapy. 2018 Sep;18(9):983-988.
Kanungo S, Chatterjee P. Oral cholera vaccines: exploring the farrago of evidence. The Lancet Infectious Diseases. 2017 Oct 1;17(10):1012-3.

Policy Papers

Dutta S, Deb AK, Chatterjee P. Adaptation Plan for Climate Sensitive Water Borne Diseases. Indian Council of Medical Research, National Institute of Cholera and Enteric Diseases; July 2018, Kolkata.
Panda S, Chatterjee P, Deb AK, Kanungo S, Dutta S. Oral Cholera Vaccines – Worth a shot? A Policy Brief. Indian Council of Medical Research, November 2017, New Delhi.

Research Posters and Presentations

Conference Title	Venue and Time	Paper Title	Authors
53^rd US-Japan Cooperative Medical Sciences Program (USJCMSP) under 21^st International Conference on Emerging Infectious Diseases in the Pacific Rim.	Hanoi, Vietnam 02/2019	Making the Case for Programmatic Implementation of Oral Cholera Vaccine in Cholera Hotspots of India.	Kanungo S, Chatterjee P, Dutta S.
53^rd US-Japan Cooperative Medical Sciences Program (USJCMSP) under 21^st International Conference on Emerging Infectious Diseases in the Pacific Rim.	Hanoi, Vietnam 02/2019	Analyzing the Gains in the Battle Against Cholera: 1990 versus 2017.	Chatterjee P, Kanungo S, Dutta S.
52nd Joint Panel Conference on Cholera and Other Bacterial Enteric Infections	Songkhla, Hat Yai, Thailand. 02/2018	Antibiotic resistant cholera outbreaks in India (2009-2017): Identifying hotspots and trends for informed policy responses	Chatterjee P, Kanungo S, Dutta S.
52nd Joint Panel Conference on Cholera and Other Bacterial Enteric Infections	Songkhla, Hat Yai, Thailand. 02/2018	Can Single Dose Based Oral Cholera Vaccine (OCV) Campaigns Combat Cholera Outbreaks in India? Evidence Synthesis for Policy Responses	Kanungo S, Chatterjee P, Dutta S.

Dr. Pranab Chatterjee MD, PhD

Understanding & Mitigating Cholera Risk in India