FQ Resistant Diarrheagenic and Commensal E. coli

Fluoroquinolone Resistance among Escherichia coli Isolated from a Facility-Based Surveillance of Diarrhea Patients attending Tertiary care Government Hospitals in Kolkata, West Bengal

Project Brief In the hospital settings of India, patients with diarrhea are frequently treated with a cocktail of antibiotics, mostly antibiotics belonging to fluoroquinolone group, as they are commonly supplied at public healthcare facilities, but studies determining the magnitude of FQ-resistance among enteric bacteria present in the gut of diarrhea patients are scanty . To address this important issue, the current study sought to assess the magnitude of FQ resistance in E. coli, both commensal and diarrheagenic in nature, isolated from the clinical samples obtained from diarrhea patients recruited through a facility-based surveillance. The hypothesis was that FQ resistance in E. coli isolated from the clinical samples of hospital admitted diarrhea patients will be indicative of existing FQ selection pressure on other enteric bacteria including gut microbiota.
My Role Co-Investigator

  • Development the protocol
  • Data analysis and interpretation
  • Manuscript writing
Project Period January 2018 – May 2018
Funding Details World Health Organization, India Country Office

₹ 650,000 (~US$10,000)